The administration of myo-inositol, D-chiro-inositol,
pinitol, and especially dibutyryl-D-chiro-inositol can restore the function of both autonomic and somatic nerves in STZ-induced diabetic neuropathy (20,21,24,36,37).
Protective effect of
pinitol against D-galactosamine-induced hepatotoxicity in rats fed on a high-fat diet.
It is reported that carob comprises a high amount of
pinitol, which has beneficial effects on human health, such as the regulation of blood glucose levels and reduction of hyperlipidemia and inflammation [37, 38].
Pinitol accumulation in mature leaves of white clover in response to water deficit.
Effects of
pinitol isolated from soybeans on glycemic control and cardiovascular risk factors in Korean patients with type II diabetes mellitus: a randomized controlled study.
Pinitol, the methylated form of DCI, was tested in a few human studies using participants with T2D.
Pinitol, an active component of kharoub, has been shown to regulate blood glucose and is especially recommended for diabetics.
Abiotic stresses induced accumulation of many compounds such as ascorbate, glutathione, [alpha]-tocopherol, betaine, proline, and other amino acids, quaternary ammonium compounds, polyamines, sucrose, polyols (mannitol, sorbitol, and
pinitol), and oligosaccharides in the affected plant [42].
They can be classified into two major types, cyclic (e.g.,
pinitol) and acyclic (e.g., mannitol).