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enamine to N Ethoxycarbonylazepine: Formation of 4, 4'-Bis(ethoxycarbonylamino)-diphenylmethane, J.C.S.
1H-NMR of ligand (PFA) revealed the presence of a single proton at 12.66 ppm due to the
enamine N-H group (Shi et al., 2005).
- Integrated drug discovery services provider
Enamine Ltd and Danish pharmaceutical company H.
Polymer materials that present hydrolysable chemical bonds along the polymer chain, such as in the amide,
enamine, ester, and urethane functional groups, present biodegradable characteristics and can also find agricultural applications.
SAMDI Tech, a provider of label-free drug discovery solutions, has partnered with
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developed an efficient, Pdcatalyzed Heck reaction in which the 2-triflate substituted aryl ketone series 74 was coupled and intramolecularly cyclized with
enamine 75 at [C.sub.4f]-[C.sub.4]/[N.sub.2]-[C.sub.3] and isomerized to produce four examples of ring-fluorinated and fluoroarylated isoquinolines 76 [49].
Ligand Docking CoCoCo_ID VENDOR (*) Fitness Score (kcal/mol) LJH68 -12.282 - - (Native Ligand) 5777208 -13.183 5777208 NCI 1.654556 1356444 -12.714 1356444 CBN 1.553880 5919607 -12.426 5919607 PRN 2.114975 1906060 -12.049 1906060 CHD 1.495216 2231818 -11.763 2231818 CHD, PRN 1.765809 6739988 -11.693 6739988 PRN 2.137922 810148 -11.680 810148 CBE, PRN 2.073499 5923852 -11.654 5923852 PRN 2.100553 1963198 -11.420 1963198 CHD 1.544532 4501898 -11.018 4501898 ENM 1.548856 1384260 -11.011 1384260 CBN 1.763145 416963 -10.834 416963 ANG, CHD 1.909153 (*) NCI: National Cancer Institute; CBE/CBN: ChemBridge; PRN: Princeton Biomolecular Research Inc; CHD: ChemDiv; ENM:
Enamine.
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