mutate

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mu·tate

(myo͞o′tāt, myo͞o-tāt′)

intr. & tr.v. mu·tat·ed, mu·tat·ing, mu·tates

To undergo or cause to undergo mutation.

[Latin mūtāre, mūtāt-, to change; see mei- in Indo-European roots.]

mu′ta′tive (-tā′tĭv, -tə-tĭv) adj.

mu′ta′tor n.

American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

mutate

(mjuːˈteɪt)

(Genetics) to undergo or cause to undergo mutation

[C19: from Latin mūtātus changed, from mūtāre to change]

mutative adj

Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014

mu•tate

(ˈmyu teɪt)

v. -tat•ed, -tat•ing. v.i.

1. to undergo mutation.

v.t.

2. to cause to undergo mutation.

[1810–20; < Latin mūtātus, past participle of mūtare to change; see -ate¹]

mu′ta•tive (-tə tɪv) adj.

mutate

Past participle: mutated
Gerund: mutating

Imperative
mutate
mutate

Present
I mutate
you mutate
he/she/it mutates
we mutate
you mutate
they mutate

Preterite
I mutated
you mutated
he/she/it mutated
we mutated
you mutated
they mutated

Present Continuous
I am mutating
you are mutating
he/she/it is mutating
we are mutating
you are mutating
they are mutating

Present Perfect
I have mutated
you have mutated
he/she/it has mutated
we have mutated
you have mutated
they have mutated

Past Continuous
I was mutating
you were mutating
he/she/it was mutating
we were mutating
you were mutating
they were mutating

Past Perfect
I had mutated
you had mutated
he/she/it had mutated
we had mutated
you had mutated
they had mutated

Future
I will mutate
you will mutate
he/she/it will mutate
we will mutate
you will mutate
they will mutate

Future Perfect
I will have mutated
you will have mutated
he/she/it will have mutated
we will have mutated
you will have mutated
they will have mutated

Future Continuous
I will be mutating
you will be mutating
he/she/it will be mutating
we will be mutating
you will be mutating
they will be mutating

Present Perfect Continuous
I have been mutating
you have been mutating
he/she/it has been mutating
we have been mutating
you have been mutating
they have been mutating

Future Perfect Continuous
I will have been mutating
you will have been mutating
he/she/it will have been mutating
we will have been mutating
you will have been mutating
they will have been mutating

Past Perfect Continuous
I had been mutating
you had been mutating
he/she/it had been mutating
we had been mutating
you had been mutating
they had been mutating

Conditional
I would mutate
you would mutate
he/she/it would mutate
we would mutate
you would mutate
they would mutate

Past Conditional
I would have mutated
you would have mutated
he/she/it would have mutated
we would have mutated
you would have mutated
they would have mutated

Collins English Verb Tables © HarperCollins Publishers 2011

ThesaurusAntonymsRelated WordsSynonymsLegend:

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Verb

mutate - undergo mutation; "cells mutate"

change - undergo a change; become different in essence; losing one's or its original nature; "She changed completely as she grew older"; "The weather changed last night"

revert - undergo reversion, as in a mutation

mutate

verb change, convert, transform, evolve, metamorphose, transmute, transfigure Overnight, the gossip begins to mutate into headlines.

Collins Thesaurus of the English Language – Complete and Unabridged 2nd Edition. 2002 © HarperCollins Publishers 1995, 2002

mutate

verb

1. To make or become different:

alter, change, modify, turn, vary.

2. To change into a different form, substance, or state:

convert, metamorphose, transfigure, transform, translate, transmogrify, transmute, transpose, transubstantiate.

Translations

mutatoidamutatoitua

mutante mutare mutazione

mutate

[mjuːˈteɪt]

A. VT (Bio) → mutar; (= change) → transformar

B. VI (Bio) → mutarse, sufrir mutación; (= change) → transformarse

Collins Spanish Dictionary - Complete and Unabridged 8th Edition 2005 © William Collins Sons & Co. Ltd. 1971, 1988 © HarperCollins Publishers 1992, 1993, 1996, 1997, 2000, 2003, 2005

mutate

[mjuːˈteɪt] vi → subir une mutation

Collins English/French Electronic Resource. © HarperCollins Publishers 2005

mutate

vi → sich verändern; (Biol) → mutieren (to zu); (Ling) → sich verwandeln (→ to in +acc); to mutate into something (fig) → sich in etw (acc) → verwandeln

vt → wandeln; (Biol) → zu einer Mutation führen bei

Collins German Dictionary – Complete and Unabridged 7th Edition 2005. © William Collins Sons & Co. Ltd. 1980 © HarperCollins Publishers 1991, 1997, 1999, 2004, 2005, 2007

mutate

[mjuːˈteɪt] vi → subire una mutazione

References in periodicals archive ?

If the INSPIRE Trial is successful, we believe rigosertib could be the first new treatment for higher-risk MDS in more than 15 years, and based on its unique mechanism of action, has the potential to provide clinical benefit in other Ras mutated cancers.

Onconova reports Q2 EPS (60c), consensus (82c)

Previous research has shown that mutated MFN2 causes mitochondria to malfunction in a common type of Charcot-Marie-Tooth disease, CMT type 2A.

Protein key to charcot-marie-tooth, other nerve diseases: Study

Comparing efficacy in mutated and non-mutated cells

Testing Cells for Cancer Drug Resistance

Until now, there were no reimbursed drug treatments that offered clear benefits for these patients following surgery, and as a result, nearly half (44%) of those with BRAF V600 mutated melanoma suffer a recurrence within a year after surgery.

Cancer drug approved

Oncology company Targovax ASA (OSE:TRVX) disclosed on Monday the receipt of a patent from the European Patent Office for its Peptide mixture that protects the composition of its mutant-RAS specific neoantigen vaccine TG02 for stimulating the immune system of cancer patients with RAS mutated tumors.

Targovax ASA awarded European Patent for mutant-RAS specific neoantigen vaccine TG02

Vaccines given in 2016 were updated to fight a mutation in H3N2 - but scientists believe it has since mutated again.

Winter crisis fear as killer flu mutates

However, mutated TP53 in tumours can interfere with WT TP53 function.

TP53 binding to BRCA1 and RAD51 in MCF7 and MDA-MB-468 breast cancer cell lines in vivo and in vitro

-- A mutated fungus is infecting white pine forests in parts of New Hampshire, according to a U.S.

Mutated fungus threatens white pine trees

Overall, researchers discovered that 1 percent of the obese patients had a mutated version of the gene KSR2, which has been previously associated with regulating energy balance and metabolism in mice.

Researchers discover new gene linked to obesity

The genes, which are mutated in the case of myeloid leukemia patients, were found to suppress growth of cancer cells through extracorporeal experiments, the researchers of the University of Tokyo, Kyoto University and other institutions said.

Researchers identify genes suppressing myeloid leukemia

The drugs, by halting or slowing growth of some cancer cells, may have left room for small groups of already mutated or newly mutated cells to take over the tumor.

Cancer treatment questioned

An enzyme that naturally occurs in the brain helps destroy the mutated protein that is the most common cause of inherited Parkinson's disease.